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UNC-89 (obscurin) binds to MEL-26, a BTB-domain protein, and affects the function of MEI-1 (katanin) in striated muscle of Caenorhabditis elegans

The ubiquitin proteasome system is involved in degradation of old or damaged sarcomeric proteins. Most E3 ubiquitin ligases are associated with cullins, which function as scaffolds for assembly of the protein degradation machinery. Cullin 3 uses an adaptor to link to substrates; in Caenorhabditis el...

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Detalles Bibliográficos
Autores principales: Wilson, Kristy J., Qadota, Hiroshi, Mains, Paul E., Benian, Guy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395652/
https://www.ncbi.nlm.nih.gov/pubmed/22621901
http://dx.doi.org/10.1091/mbc.E12-01-0055

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