Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation

Mammalian cells secrete a large number of small proteins, but their mode of translocation into the endoplasmic reticulum is not fully understood. Cotranslational translocation was expected to be inefficient due to the small time window for signal sequence recognition by the signal recognition partic...

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Detalles Bibliográficos
Autores principales: Lakkaraju, Asvin K. K., Thankappan, Ratheeshkumar, Mary, Camille, Garrison, Jennifer L., Taunton, Jack, Strub, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395660/
https://www.ncbi.nlm.nih.gov/pubmed/22648169
http://dx.doi.org/10.1091/mbc.E12-03-0228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395660/
https://www.ncbi.nlm.nih.gov/pubmed/22648169
http://dx.doi.org/10.1091/mbc.E12-03-0228

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