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Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation
Mammalian cells secrete a large number of small proteins, but their mode of translocation into the endoplasmic reticulum is not fully understood. Cotranslational translocation was expected to be inefficient due to the small time window for signal sequence recognition by the signal recognition partic...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395660/ https://www.ncbi.nlm.nih.gov/pubmed/22648169 http://dx.doi.org/10.1091/mbc.E12-03-0228 |