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Dynamic Changes in Ezh2 Gene Occupancy Underlie Its Involvement in Neural Stem Cell Self-Renewal and Differentiation towards Oligodendrocytes

BACKGROUND: The polycomb group protein Ezh2 is an epigenetic repressor of transcription originally found to prevent untimely differentiation of pluripotent embryonic stem cells. We previously demonstrated that Ezh2 is also expressed in multipotent neural stem cells (NSCs). We showed that Ezh2 expres...

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Detalles Bibliográficos
Autores principales:	Sher, Falak, Boddeke, Erik, Olah, Marta, Copray, Sjef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395718/ https://www.ncbi.nlm.nih.gov/pubmed/22808153 http://dx.doi.org/10.1371/journal.pone.0040399

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