Cargando…

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase a oncogene

BACKGROUND: Protein tyrosine phosphatase receptor delta (PTPRD) is a member of a large family of protein tyrosine phosphatases which negatively regulate tyrosine phosphorylation. Neuroblastoma is a major childhood cancer arising from precursor cells of the sympathetic nervous system which is known t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meehan, Maria, Parthasarathi, Laavanya, Moran, Niamh, Jefferies, Caroline A, Foley, Niamh, Lazzari, Elisa, Murphy, Derek, Ryan, Jacqueline, Ortiz, Berenice, M Fabius, Armida W, Chan, Timothy A, Stallings, Raymond L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395855/ https://www.ncbi.nlm.nih.gov/pubmed/22305495 http://dx.doi.org/10.1186/1476-4598-11-6

Ejemplares similares

Expressional alterations in functional ultra-conserved non-coding rnas in response to all-trans retinoic acid - induced differentiation in neuroblastoma cells
por: Watters, Karen M, et al.
Publicado: (2013)

Physiological and Oncogenic Aurora-A Pathway
por: SAEKI, Toshiaki, et al.
Publicado: (2009)

Aurora Kinases as Targets in Drug-Resistant Neuroblastoma Cells
por: Michaelis, Martin, et al.
Publicado: (2014)

MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2
por: Foley, Niamh H, et al.
Publicado: (2010)

Analysis of Protein Phosphatase-1 and Aurora Protein Kinase Suppressors Reveals New Aspects of Regulatory Protein Function in Saccharomyces cerevisiae
por: Ghosh, Anuprita, et al.
Publicado: (2013)

Global MYCN Transcription Factor Binding Analysis in Neuroblastoma Reveals Association with Distinct E-Box Motifs and Regions of DNA Hypermethylation
por: Murphy, Derek M., et al.
Publicado: (2009)

Loss of CASZ1 tumor suppressor linked to oncogenic subversion of neuroblastoma core regulatory circuitry
por: Liu, Zhihui, et al.
Publicado: (2022)

Aurora kinase A is a possible target of OSU-03012 to destabilize MYC family proteins
por: SILVA, ANDRES, et al.
Publicado: (2014)

MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma
por: Tivnan, Amanda, et al.
Publicado: (2011)

Involvement of protein phosphatases in the destabilization of methamphetamine-associated contextual memory
por: Yu, Yang-Jung, et al.
Publicado: (2016)

A Large Scale shRNA Barcode Screen Identifies the Circadian Clock Component ARNTL as Putative Regulator of the p53 Tumor Suppressor Pathway
por: Mullenders, Jasper, et al.
Publicado: (2009)

Deficiency of BAP1 inhibits neuroblastoma tumorigenesis through destabilization of MYCN
por: Zhang, Xiaoling, et al.
Publicado: (2023)

Dual roles of oxostephanine as an Aurora kinase inhibitor and angiogenesis suppressor
por: Tran, Thu-Hien Thi, et al.
Publicado: (2022)

Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity
por: Gehring, Kalle, et al.
Publicado: (2020)

Aurora Borealis (Bora), Which Promotes Plk1 Activation by Aurora A, Has an Oncogenic Role in Ovarian Cancer
por: Parrilla, Alfonso, et al.
Publicado: (2020)

The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways
por: Lu, Xiongbin, et al.
Publicado: (2008)

Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma
por: Bogen, Dominik, et al.
Publicado: (2015)

IRF2 Destabilizes Oncogenic KPNA2 to Modulate the Development of Osteosarcoma
por: Xia, Shuchi, et al.
Publicado: (2022)

The Protein Phosphatase PPM1G Destabilizes HIF-1α Expression
por: Pyo, Jaehyuk, et al.
Publicado: (2018)

Nuclear Aurora kinase A switches m(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4
por: Li, SiSi, et al.
Publicado: (2022)

Bistability of a coupled Aurora B kinase-phosphatase system in cell division
por: Zaytsev, Anatoly V, et al.
Publicado: (2016)

HIV infection destabilizes a targeted subset of the gamma/delta T cell repertoire
por: Hebbeler, Andrew M, et al.
Publicado: (2006)

Modulation of Neuroblastoma Disease Pathogenesis By An Extensive Network of Epigenetically Regulated MicroRNAs
por: Das, Sudipto, et al.
Publicado: (2012)

The Novel Phosphatase Domain Mutations Q171R and Y65S Switch PTEN from Tumor Suppressor to Oncogene
por: Garrido, Jose Antonio Ma. G., et al.
Publicado: (2021)

Tumor-Suppressor Genes and Oncogenes
Publicado: (1993)

Oncogenes and tumor-suppressor genes.
por: Lehman, T A, et al.
Publicado: (1991)

Loss of tumor suppressor inositol polyphosphate 4-phosphatase type B impairs DNA double-strand break repair by destabilization of DNA tethering protein Rad50
por: Sun, Yue, et al.
Publicado: (2020)

CX, DPX and PRIDE: WWW servers for the analysis and comparison of protein 3D structures
por: Vlahoviček, Kristian, et al.
Publicado: (2005)

ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer
por: Ji, Shunrong, et al.
Publicado: (2015)

Co-Localization of the Oncogenic Transcription Factor MYCN and the DNA Methyl Binding Protein MeCP2 at Genomic Sites in Neuroblastoma
por: Murphy, Derek M., et al.
Publicado: (2011)

Widespread Dysregulation of MiRNAs by MYCN Amplification and Chromosomal Imbalances in Neuroblastoma: Association of miRNA Expression with Survival
por: Bray, Isabella, et al.
Publicado: (2009)

Macrophage phenotypes and monocyte subsets after destabilization of the medial meniscus in mice
por: Utomo, Lizette, et al.
Publicado: (2020)

Ghrelin Upregulates Oncogenic Aurora A to Promote Renal Cell Carcinoma Invasion
por: Lin, Tsung-Chieh, et al.
Publicado: (2019)

Neuroblastoma: oncogenic mechanisms and therapeutic exploitation of necroptosis
por: Nicolai, S, et al.
Publicado: (2015)

Expression of ret Proto‐oncogene in Human Neuroblastomas
por: Nagao, Minako, et al.
Publicado: (1990)

Linc01105 acts as an oncogene in the development of neuroblastoma
por: Ye, Mujie, et al.
Publicado: (2021)

Dual-Specificity Phosphatases in Neuroblastoma Cell Growth and Differentiation
por: Nunes-Xavier, Caroline E., et al.
Publicado: (2019)

Genomic-Destabilization-Associated Mutagenesis and Clonal Evolution of Cells with Mutations in Tumor-Suppressor Genes
por: Yoshioka, Ken-ichi, et al.
Publicado: (2019)

The role of epigenetics and miRNAs in neuroblastoma development
por: Rupani, KV, et al.
Publicado: (2012)

A giant duodenal diverticulum causing Lemmel syndrome
por: Tobin, Roseanne, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_24p88kv1keh1ie1m7do0pg4r73