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In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution

BACKGROUND: In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, th...

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Autores principales: Waizy, Hazibullah, Weizbauer, Andreas, Modrejewski, Christian, Witte, Frank, Windhagen, Henning, Lucas, Arne, Kieke, Marc, Denkena, Berend, Behrens, Peter, Meyer-Lindenberg, Andrea, Bach, Friedrich-Wilhelm, Thorey, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395858/
https://www.ncbi.nlm.nih.gov/pubmed/22413949
http://dx.doi.org/10.1186/1475-925X-11-12
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author Waizy, Hazibullah
Weizbauer, Andreas
Modrejewski, Christian
Witte, Frank
Windhagen, Henning
Lucas, Arne
Kieke, Marc
Denkena, Berend
Behrens, Peter
Meyer-Lindenberg, Andrea
Bach, Friedrich-Wilhelm
Thorey, Fritz
author_facet Waizy, Hazibullah
Weizbauer, Andreas
Modrejewski, Christian
Witte, Frank
Windhagen, Henning
Lucas, Arne
Kieke, Marc
Denkena, Berend
Behrens, Peter
Meyer-Lindenberg, Andrea
Bach, Friedrich-Wilhelm
Thorey, Fritz
author_sort Waizy, Hazibullah
collection PubMed
description BACKGROUND: In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and removal of the implant after surgery. METHODS: ZEK100 plates were examined in this in vitro study with Hank's Balanced Salt Solution under physiological conditions with a constant laminar flow rate. After 14, 28 and 42 days of immersion the ZEK100 plates were mechanically tested via four point bending test. The surfaces of the immersed specimens were characterized by SEM, EDX and XRD. RESULTS: The four point bending test displayed an increased bending strength after 6 weeks immersion compared to the 2 week group and 4 week group. The characterization of the surface revealed the presence of high amounts of O, P and Ca on the surface and small Mg content. This indicates the precipitation of calcium phosphates with low solubility on the surface of the ZEK100 plates. CONCLUSIONS: The results of the present in vitro study indicate that ZEK100 is a potential candidate for degradable orthopedic implants. Further investigations are needed to examine the degradation behavior.
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spelling pubmed-33958582012-07-16 In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution Waizy, Hazibullah Weizbauer, Andreas Modrejewski, Christian Witte, Frank Windhagen, Henning Lucas, Arne Kieke, Marc Denkena, Berend Behrens, Peter Meyer-Lindenberg, Andrea Bach, Friedrich-Wilhelm Thorey, Fritz Biomed Eng Online Research BACKGROUND: In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and removal of the implant after surgery. METHODS: ZEK100 plates were examined in this in vitro study with Hank's Balanced Salt Solution under physiological conditions with a constant laminar flow rate. After 14, 28 and 42 days of immersion the ZEK100 plates were mechanically tested via four point bending test. The surfaces of the immersed specimens were characterized by SEM, EDX and XRD. RESULTS: The four point bending test displayed an increased bending strength after 6 weeks immersion compared to the 2 week group and 4 week group. The characterization of the surface revealed the presence of high amounts of O, P and Ca on the surface and small Mg content. This indicates the precipitation of calcium phosphates with low solubility on the surface of the ZEK100 plates. CONCLUSIONS: The results of the present in vitro study indicate that ZEK100 is a potential candidate for degradable orthopedic implants. Further investigations are needed to examine the degradation behavior. BioMed Central 2012-03-13 /pmc/articles/PMC3395858/ /pubmed/22413949 http://dx.doi.org/10.1186/1475-925X-11-12 Text en Copyright ©2012 Waizy et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Waizy, Hazibullah
Weizbauer, Andreas
Modrejewski, Christian
Witte, Frank
Windhagen, Henning
Lucas, Arne
Kieke, Marc
Denkena, Berend
Behrens, Peter
Meyer-Lindenberg, Andrea
Bach, Friedrich-Wilhelm
Thorey, Fritz
In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution
title In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution
title_full In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution
title_fullStr In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution
title_full_unstemmed In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution
title_short In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution
title_sort in vitro corrosion of zek100 plates in hank's balanced salt solution
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395858/
https://www.ncbi.nlm.nih.gov/pubmed/22413949
http://dx.doi.org/10.1186/1475-925X-11-12
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