Cholinergic Abnormalities, Endosomal Alterations and Up-Regulation of Nerve Growth Factor Signaling in Niemann-Pick Type C Disease

BACKGROUND: Neurotrophins and their receptors regulate several aspects of the developing and mature nervous system, including neuronal morphology and survival. Neurotrophin receptors are active in signaling endosomes, which are organelles that propagate neurotrophin signaling along neuronal processe...

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Detalles Bibliográficos
Autores principales: Cabeza, Carolina, Figueroa, Alicia, Lazo, Oscar M, Galleguillos, Carolina, Pissani, Claudia, Klein, Andrés, Gonzalez-Billault, Christian, Inestrosa, Nibaldo C, Alvarez, Alejandra R, Zanlungo, Silvana, Bronfman, Francisca C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395862/
https://www.ncbi.nlm.nih.gov/pubmed/22458984
http://dx.doi.org/10.1186/1750-1326-7-11

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