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Post Partum Depression and Thyroid Function
OBJECTIVE: Risk of depression is particularly high for women during the prenatal period. Various investigators have attempted to establish a link between thyroid function and post partum depression. This study aimed to investigate whether thyroid function differs in women with postpartum depression...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tehran University of Medical Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395948/ https://www.ncbi.nlm.nih.gov/pubmed/22952534 |
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author | Keshavarzi, Farahnaz Yazdchi, Katayoun Rahimi, Mehrali Rezaei, Mansour Farnia, Vahid Davarinejad, Omran Abdoli, Nasrin Jalili, Mahmood |
author_facet | Keshavarzi, Farahnaz Yazdchi, Katayoun Rahimi, Mehrali Rezaei, Mansour Farnia, Vahid Davarinejad, Omran Abdoli, Nasrin Jalili, Mahmood |
author_sort | Keshavarzi, Farahnaz |
collection | PubMed |
description | OBJECTIVE: Risk of depression is particularly high for women during the prenatal period. Various investigators have attempted to establish a link between thyroid function and post partum depression. This study aimed to investigate whether thyroid function differs in women with postpartum depression compared to a control group. METHODS: In this case-control study, subjects were selected from Obstetrics & Gynecology and Psychiatric clinics of Kermanshah University of Medical Sciences. Forty eight patients suffering from postpartum depression according to Diagnostic and Statistical Manual of Mental Disorders, fourth edition totally revised (DSM-IV-TR), and 65 normal controls underwent diagnostic evaluation by one trained psychiatrist using Structured Clinical Interview for DSM-IV-TR. Then, the demographic questionnaire and the Persian version of Edinburgh Postnatal Depression Scale (EPDS) were completed by the participants. Finally, their thyroid functions were assessed. Data analyses were done using the SPSS program 13. RESULTS: No statistically significant differences were observed between thyroid function tests and postpartum depression. According to multiple regression analysis with stepwise method, subjects with lower serum TSH, T3RU, T3 levels, younger age and longer period after delivery tended to have higher EPDS scores (P-value=0.008). CONCLUSION: The present study reports that those women with postpartum depression had a no greater prevalence of thyroid dysfunction than the control subjects. It seems that thyroid dysfunction should be considered in women with postpartum depression individually, but the role of thyroid as an important cause of this condition is not yet established. This suggests that future studies should concentrate on this concept in postpartum depression. |
format | Online Article Text |
id | pubmed-3395948 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-33959482012-09-05 Post Partum Depression and Thyroid Function Keshavarzi, Farahnaz Yazdchi, Katayoun Rahimi, Mehrali Rezaei, Mansour Farnia, Vahid Davarinejad, Omran Abdoli, Nasrin Jalili, Mahmood Iran J Psychiatry Original Article OBJECTIVE: Risk of depression is particularly high for women during the prenatal period. Various investigators have attempted to establish a link between thyroid function and post partum depression. This study aimed to investigate whether thyroid function differs in women with postpartum depression compared to a control group. METHODS: In this case-control study, subjects were selected from Obstetrics & Gynecology and Psychiatric clinics of Kermanshah University of Medical Sciences. Forty eight patients suffering from postpartum depression according to Diagnostic and Statistical Manual of Mental Disorders, fourth edition totally revised (DSM-IV-TR), and 65 normal controls underwent diagnostic evaluation by one trained psychiatrist using Structured Clinical Interview for DSM-IV-TR. Then, the demographic questionnaire and the Persian version of Edinburgh Postnatal Depression Scale (EPDS) were completed by the participants. Finally, their thyroid functions were assessed. Data analyses were done using the SPSS program 13. RESULTS: No statistically significant differences were observed between thyroid function tests and postpartum depression. According to multiple regression analysis with stepwise method, subjects with lower serum TSH, T3RU, T3 levels, younger age and longer period after delivery tended to have higher EPDS scores (P-value=0.008). CONCLUSION: The present study reports that those women with postpartum depression had a no greater prevalence of thyroid dysfunction than the control subjects. It seems that thyroid dysfunction should be considered in women with postpartum depression individually, but the role of thyroid as an important cause of this condition is not yet established. This suggests that future studies should concentrate on this concept in postpartum depression. Tehran University of Medical Sciences 2011 /pmc/articles/PMC3395948/ /pubmed/22952534 Text en © 2011 Psychiatry and Psychology Research Center, Tehran University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly. |
spellingShingle | Original Article Keshavarzi, Farahnaz Yazdchi, Katayoun Rahimi, Mehrali Rezaei, Mansour Farnia, Vahid Davarinejad, Omran Abdoli, Nasrin Jalili, Mahmood Post Partum Depression and Thyroid Function |
title | Post Partum Depression and Thyroid Function |
title_full | Post Partum Depression and Thyroid Function |
title_fullStr | Post Partum Depression and Thyroid Function |
title_full_unstemmed | Post Partum Depression and Thyroid Function |
title_short | Post Partum Depression and Thyroid Function |
title_sort | post partum depression and thyroid function |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395948/ https://www.ncbi.nlm.nih.gov/pubmed/22952534 |
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