Cargando…
Insulin-Like Growth Factor Binding Proteins-3 and -5: Central Mediators of Fibrosis and Promising New Therapeutic Targets
Fibrosis involves an orchestrated cascade of events including activation of fibroblasts, increased production and deposition of extracellular matrix components, and differentiation of fibroblasts into myofibroblasts. Epithelial-mesenchymal cross-talk plays an important role in this process, and curr...
Autores principales: | Veraldi, Kristen L, Feghali-Bostwick, Carol A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395973/ https://www.ncbi.nlm.nih.gov/pubmed/22802912 http://dx.doi.org/10.2174/1874312901206010140 |
Ejemplares similares
-
Insulin-like growth factor (IGF)-II- mediated fibrosis in pathogenic lung conditions
por: Garrett, Sara M., et al.
Publicado: (2019) -
Syndecan-2 Is a Novel Target of Insulin-Like Growth Factor Binding Protein-3 and Is Over-Expressed in Fibrosis
por: Ruiz, Ximena D., et al.
Publicado: (2012) -
Human Skin Culture as an Ex Vivo Model for Assessing the Fibrotic Effects of Insulin-Like Growth Factor Binding Proteins
por: Yasuoka, Hidekata, et al.
Publicado: (2008) -
Fibroblasts in fibrosis: novel roles and mediators
por: Kendall, Ryan T., et al.
Publicado: (2014) -
Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5
por: Nguyen, Xinh-Xinh, et al.
Publicado: (2021)