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Ethyl pyruvate for the treatment of acetaminophen intoxication: alternative to N-acetylcysteine?
N-acetylcysteine is the classical antidote for acetaminophen overdose-induced hepatotoxicity, but its efficacy is limited by the need for early and only temporary treatment. Therefore, Yang and colleagues tested the hypothesis of whether ethyl pyruvate - another anti-inflammatory and antioxidant com...
Autores principales: | Wagner, Florian, Asfar, Pierre, Georgieff, Michael, Radermacher, Peter, Wagner, Katja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396244/ https://www.ncbi.nlm.nih.gov/pubmed/22348679 http://dx.doi.org/10.1186/cc11153 |
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