Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trial

INTRODUCTION: Although early use of broad-spectrum antimicrobials in critically ill patients may increase antimicrobial adequacy, uncontrolled use of these agents may select for more-resistant organisms. This study investigated the effects of early use of broad-spectrum antimicrobials in critically...

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Detalles Bibliográficos
Autores principales: Kim, Jong Wook, Chung, Joowon, Choi, Sang-Ho, Jang, Hang Jea, Hong, Sang-Bum, Lim, Chae-Man, Koh, Younsuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396273/
https://www.ncbi.nlm.nih.gov/pubmed/22336530
http://dx.doi.org/10.1186/cc11197

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