An MRI-visible non-viral vector for targeted Bcl-2 siRNA delivery to neuroblastoma

Polyethylene glycol-grafted polyethylenimine (PEG-g-PEI) which was functionalized with a neuroblastoma cell-specific ligand, the GD2 single chain antibody (scAb(GD2)), was synthesized in order to effectively deliver Bcl-2 siRNA into neuroblastoma cells. This polymer was complexed first with superpar...

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Detalles Bibliográficos
Autores principales: Shen, Min, Gong, Faming, Pang, Pengfei, Zhu, Kangshun, Meng, Xiaochun, Wu, Chun, Wang, Jin, Shan, Hong, Shuai, Xintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396391/
https://www.ncbi.nlm.nih.gov/pubmed/22802690
http://dx.doi.org/10.2147/IJN.S32900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396391/
https://www.ncbi.nlm.nih.gov/pubmed/22802690
http://dx.doi.org/10.2147/IJN.S32900

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