Cargando…

An MRI-visible non-viral vector for targeted Bcl-2 siRNA delivery to neuroblastoma

Polyethylene glycol-grafted polyethylenimine (PEG-g-PEI) which was functionalized with a neuroblastoma cell-specific ligand, the GD2 single chain antibody (scAb(GD2)), was synthesized in order to effectively deliver Bcl-2 siRNA into neuroblastoma cells. This polymer was complexed first with superpar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Min, Gong, Faming, Pang, Pengfei, Zhu, Kangshun, Meng, Xiaochun, Wu, Chun, Wang, Jin, Shan, Hong, Shuai, Xintao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396391/ https://www.ncbi.nlm.nih.gov/pubmed/22802690 http://dx.doi.org/10.2147/IJN.S32900

Ejemplares similares

An RGD-Modified MRI-Visible Polymeric Vector for Targeted siRNA Delivery to Hepatocellular Carcinoma in Nude Mice
por: Wu, Chun, et al.
Publicado: (2013)

An MRI-Visible Non-Viral Vector Bearing GD2 Single Chain Antibody for Targeted Gene Delivery to Human Bone Marrow Mesenchymal Stem Cells
por: Pang, Pengfei, et al.
Publicado: (2013)

Development of an MRI-visible nonviral vector for siRNA delivery targeting gastric cancer
por: Chen, Yinting, et al.
Publicado: (2012)

Local siRNA delivery by non-viral vectors
por: Beilvert, F., et al.
Publicado: (2012)

Enhanced apoptosis of ovarian cancer cells via nanocarrier-mediated codelivery of siRNA and doxorubicin
por: Zou, Seyin, et al.
Publicado: (2012)

Prospects of Cationic Carbosilane Dendronized Gold Nanoparticles as Non-viral Vectors for Delivery of Anticancer siRNAs siBCL-xL and siMCL-1
por: Abashkin, Viktar, et al.
Publicado: (2021)

Non-viral siRNA delivery to the lung()
por: Thomas, Mini, et al.
Publicado: (2007)

The MRI-Visible Nanocomposite Facilitates the Delivery and Tracking of siRNA Loaded DC Vaccine in the Breast Cancer Model
por: Wu, Changqiang, et al.
Publicado: (2021)

Nanoparticle-Mediated Systemic Delivery of siRNA for Treatment of Cancers and Viral Infections
por: Draz, Mohamed Shehata, et al.
Publicado: (2014)

Codelivery of temozolomide and siRNA with polymeric nanocarrier for effective glioma treatment
por: Peng, Yuan, et al.
Publicado: (2018)

Functionalized non-viral cationic vectors for effective siRNA induced cancer therapy
por: Gupta, Kshitij, et al.
Publicado: (2017)

Research Status and Prospect of Non-Viral Vectors Based on siRNA: A Review
por: Tong, Liangnan, et al.
Publicado: (2023)

Selection and Incorporation of siRNA Carrying Non-Viral Vector for Sustained Delivery from Gellan Gum Hydrogels
por: Nalbadis, Anastasios, et al.
Publicado: (2021)

Non-viral siRNA delivery into the mouse retina in vivo
por: Turchinovich, Andrey, et al.
Publicado: (2010)

Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery
por: Slita, Anna, et al.
Publicado: (2018)

Target delivery of MYCN siRNA by folate-nanoliposomes delivery system in a metastatic neuroblastoma model
por: Zhu, Qiqi, et al.
Publicado: (2013)

Polyethylenimine-Conjugated Hydroxyethyl Cellulose for Doxorubicin/Bcl-2 siRNA Co-Delivery Systems
por: Park, Jiwon, et al.
Publicado: (2023)

Calcium phosphate nanoparticles-based systems for siRNA delivery
por: Xu, Xiaochun, et al.
Publicado: (2016)

Structural and Functional Analysis of Viral siRNAs
por: Szittya, Gyorgy, et al.
Publicado: (2010)

Application of quantum dots as vectors in targeted survivin gene siRNA delivery
por: Zhao, Jianjiang, et al.
Publicado: (2013)

The investigation of polymer-siRNA nanoparticle for gene therapy of gastric cancer in vitro
por: Wu, Ying, et al.
Publicado: (2010)

Targeted Delivery of siRNA
por: Oliveira, Sabrina, et al.
Publicado: (2006)

Dendrimers for siRNA Delivery
por: Biswas, Swati, et al.
Publicado: (2013)

Therapy of Respiratory Viral Infections with Intranasal siRNAs
por: Barik, Sailen, et al.
Publicado: (2014)

Preparation and Preliminary Evaluation of Dual-functional Nanoparticles for MRI and siRNA Delivery
por: Sun, Jingxin, et al.
Publicado: (2021)

Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers
por: Thakur, Ajit, et al.
Publicado: (2012)

Progress in non-viral localized delivery of siRNA therapeutics for pulmonary diseases
por: Gao, Jingjing, et al.
Publicado: (2023)

Gene expression profiles in BCL11B-siRNA treated malignant T cells
por: Huang, Xin, et al.
Publicado: (2011)

Chitosan Hydrogel as siRNA vector for prolonged gene silencing
por: Ma, Zhiwei, et al.
Publicado: (2014)

Novel Targeted Therapy for Neuroblastoma: Silencing the MXD3 Gene Using siRNA
por: Duong, Connie, et al.
Publicado: (2017)

Lentivirus-mediated siRNA knockdown of SPHK1 inhibits proliferation and tumorigenesis of neuroblastoma
por: Su, Lin, et al.
Publicado: (2018)

Glycol chitosan nanoparticles as specialized cancer therapeutic vehicles: Sequential delivery of doxorubicin and Bcl-2 siRNA
por: Yoon, Hong Yeol, et al.
Publicado: (2014)

Inhibition of cell proliferation through an ATP-responsive co-delivery system of doxorubicin and Bcl-2 siRNA
por: Zhang, Jianxu, et al.
Publicado: (2017)

RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model
por: Lee, Tae Jin, et al.
Publicado: (2015)

ATP-activated decrosslinking and charge-reversal vectors for siRNA delivery and cancer therapy
por: Zhou, Zhanwei, et al.
Publicado: (2018)

Polythiophenes with Cationic Phosphonium Groups as Vectors for Imaging, siRNA Delivery, and Photodynamic Therapy
por: Lichon, Laure, et al.
Publicado: (2020)

High-Yield Synthesis of Monomeric LMWP(CPP)-siRNA Covalent Conjugate for Effective Cytosolic Delivery of siRNA
por: Ye, Junxiao, et al.
Publicado: (2017)

Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells
por: KUNZE, DOREEN, et al.
Publicado: (2012)

Aptamer mediated siRNA delivery
por: Chu, Ted C., et al.
Publicado: (2006)

Pulmonary delivery of therapeutic siRNA
por: Lam, Jenny Ka-Wing, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_v5hl1ufdbfnsb68jqh8i9m4i9o