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Safety and efficacy of ocrelizumab in combination with methotrexate in MTX-naive subjects with rheumatoid arthritis: the phase III FILM trial

OBJECTIVE: To determine the efficacy and safety of ocrelizumab (OCR) with methotrexate (MTX) in MTX-naive rheumatoid arthritis (RA) patients. METHODS: In a randomised, double-blind, controlled trial, patients received placebo+MTX (MTX; n=210), OCR 200 mg×2+MTX (OCR 200; n=200) or OCR 500 mg×2+MTX (O...

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Detalles Bibliográficos
Autores principales: Stohl, William, Gomez-Reino, Juan, Olech, Ewa, Dudler, Jean, Fleischmann, Roy M, Zerbini, Cristiano A F, Ashrafzadeh, Ali, Grzeschik, Susanna, Bieraugel, Rebecca, Green, Jennifer, Francom, Steven, Dummer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396459/
https://www.ncbi.nlm.nih.gov/pubmed/22307942
http://dx.doi.org/10.1136/annrheumdis-2011-200706

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