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Toll-Like Receptor (TLR) 2 and TLR4 Differentially Regulate Doxorubicin Induced Cardiomyopathy in Mice

Recent evidence indicates that toll-like receptor (TLR) 2 and 4 are involved in the pathogenesis of dilated cardiomyopathy (DCM), but the exact mechanisms of their actions have not been elucidated. We explored the therapeutic potential of blocking TLRs in mice with established cardiomyopathy. Cardio...

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Detalles Bibliográficos
Autores principales:	Ma, Yonggang, Zhang, Xiaowei, Bao, Huayan, Mi, Su, Cai, Wenfeng, Yan, Huimin, Wang, Qingqing, Wang, Ziyan, Yan, Jun, Fan, Guochang, Lindsey, Merry L., Hu, Zhuowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396603/ https://www.ncbi.nlm.nih.gov/pubmed/22808256 http://dx.doi.org/10.1371/journal.pone.0040763

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