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Phevalin (aureusimine B)Production by Staphylococcus aureus Biofilm and Impacts on Human Keratinocyte Gene Expression

Staphylococcus aureus biofilms are associated with chronic skin infections and are orders of magnitude more resistant to antimicrobials and host responses. S. aureus contains conserved nonribosomal peptide synthetases that produce the cyclic dipeptides tyrvalin and phevalin (aureusimine A and B, res...

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Detalles Bibliográficos
Autores principales: Secor, Patrick R., Jennings, Laura K., James, Garth A., Kirker, Kelly R., Pulcini, Elinor deLancey, McInnerney, Kate, Gerlach, Robin, Livinghouse, Tom, Hilmer, Jonathan K., Bothner, Brian, Fleckman, Philip, Olerud, John E., Stewart, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396627/
https://www.ncbi.nlm.nih.gov/pubmed/22808288
http://dx.doi.org/10.1371/journal.pone.0040973