Cargando…

Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture

In this study, we have examined the properties of synaptic transmission between dorsal root ganglion (DRG) and dorsal horn (DH) neurons, placed in co-culture. We also examined the effect of the anti-hyperalgesic gabapentinoid drug pregabalin (PGB) at this pharmacologically relevant synapse. The main...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hendrich, Janek, Bauer, Claudia S., Dolphin, Annette C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396689/ https://www.ncbi.nlm.nih.gov/pubmed/22627148 http://dx.doi.org/10.4161/chan.19805

Ejemplares similares

The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn
por: Abraira, Victoria E., et al.
Publicado: (2017)

Inhibition of NKCC1 in spinal dorsal horn and dorsal root ganglion results in alleviation of neuropathic pain in rats with spinal cord contusion
por: Wu, Yao, et al.
Publicado: (2023)

The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons
por: Lopes, Douglas M., et al.
Publicado: (2017)

Immortalized Dorsal Root Ganglion Neuron Cell Lines
por: Haberberger, Rainer Viktor, et al.
Publicado: (2020)

Modulation of GABAergic Synaptic Transmission by NMDA Receptors in the Dorsal Horn of the Spinal Cord
por: Leonardon, Benjamin, et al.
Publicado: (2022)

Characterization of dorsal root ganglion neurons cultured on silicon micro-pillar substrates
por: Repić, Tihana, et al.
Publicado: (2016)

Protocol for the isolation and culture of mouse dorsal root ganglion neurons for imaging applications
por: Smith, Patrick R., et al.
Publicado: (2023)

Synchronous firing of dorsal horn neurons at the origin of dorsal root reflexes in naïve and paw-inflamed mice
por: Lucas-Romero, Javier, et al.
Publicado: (2022)

Nerve injury increases native Ca(V)2.2 trafficking in dorsal root ganglion mechanoreceptors
por: Nieto-Rostro, Manuela, et al.
Publicado: (2023)

Pain-related synaptic plasticity in spinal dorsal horn neurons: role of CGRP
por: Bird, Gary C, et al.
Publicado: (2006)

Morphological, biophysical and synaptic properties of glutamatergic neurons of the mouse spinal dorsal horn
por: Punnakkal, Pradeep, et al.
Publicado: (2014)

Synaptic Targets of Glycinergic Neurons in Laminae I–III of the Spinal Dorsal Horn
por: Miranda, Camila Oliveira, et al.
Publicado: (2023)

Mechanism of dorsal root ganglion stimulation for pain relief in painful diabetic polyneuropathy is not dependent on GABA release in the dorsal horn of the spinal cord
por: Koetsier, Eva, et al.
Publicado: (2019)

Electroacupuncture Alleviates Diabetic Neuropathic Pain and Downregulates p-PKC and TRPV1 in Dorsal Root Ganglions and Spinal Cord Dorsal Horn
por: Ma, Yi-qi, et al.
Publicado: (2023)

Anti-allodynic and promotive effect on inhibitory synaptic transmission of riluzole in rat spinal dorsal horn
por: Taiji, Ryo, et al.
Publicado: (2021)

The upregulation of EGFR in the dorsal root ganglion contributes to chronic compression of dorsal root ganglions-induced neuropathic pain in rats
por: Wang, Shuo, et al.
Publicado: (2019)

Dissociation of μ- and δ-opioid inhibition of glutamatergic synaptic transmission in superficial dorsal horn
por: Wrigley, Paul J, et al.
Publicado: (2010)

Profile of dorsal root ganglion neurons: study of oxytocin expression
por: Noguri, Taisei, et al.
Publicado: (2022)

Platinum-Based Drugs Cause Mitochondrial Dysfunction in Cultured Dorsal Root Ganglion Neurons
por: Leo, Markus, et al.
Publicado: (2020)

Compartmentalized primary cultures of dorsal root ganglion neurons to model peripheral pathophysiological conditions
por: Giorgi, Simona, et al.
Publicado: (2023)

Synaptic Connections of the Neurokinin 1 Receptor-Like Immunoreactive Neurons in the Rat Medullary Dorsal Horn
por: Qi, Jian, et al.
Publicado: (2011)

The activation of nicotinic acetylcholine receptors enhances the inhibitory synaptic transmission in the deep dorsal horn neurons of the adult rat spinal cord
por: Takeda, Daisuke, et al.
Publicado: (2007)

Xenon inhibits excitatory but not inhibitory transmission in rat spinal cord dorsal horn neurons
por: Georgiev, Stefan K, et al.
Publicado: (2010)

An integrated cell isolation and purification method for rat dorsal root ganglion neurons
por: Shen, Huaishuang, et al.
Publicado: (2019)

ST2-Conditioned Medium Fosters Dorsal Horn Cell Excitability and Synaptic Transmission in Cultured Mouse Spinal Cord
por: Juárez, Esri H., et al.
Publicado: (2023)

Comparison of the Rat and Human Dorsal Root Ganglion Proteome
por: Schwaid, Adam G., et al.
Publicado: (2018)

Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559
por: Cheng, Long-Zhen, et al.
Publicado: (2011)

Windup of Nociceptive Flexion Reflex Depends on Synaptic and Intrinsic Properties of Dorsal Horn Neurons in Adult Rats
por: Aby, Franck, et al.
Publicado: (2019)

Modulation of chloride homeostasis by inflammatory mediators in dorsal root ganglion neurons
por: Funk, Katharina, et al.
Publicado: (2008)

Voltage-gated Na(+) currents in human dorsal root ganglion neurons
por: Zhang, Xiulin, et al.
Publicado: (2017)

Functional Expression of Piezo1 in Dorsal Root Ganglion (DRG) Neurons
por: Roh, Jueun, et al.
Publicado: (2020)

Single-nucleus transcriptomic analysis of human dorsal root ganglion neurons
por: Nguyen, Minh Q, et al.
Publicado: (2021)

Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets
por: Kudo, Moeko, et al.
Publicado: (2021)

Shared nociceptive dorsal root ganglion neurons participating in acupoint sensitization
por: Li, Wanrong, et al.
Publicado: (2022)

Palmitoylethanolamide Mitigates Paclitaxel Toxicity in Primary Dorsal Root Ganglion Neurons
por: Elfarnawany, Amira, et al.
Publicado: (2022)

Caldendrin represses neurite regeneration and growth in dorsal root ganglion neurons
por: Lopez, Josue A., et al.
Publicado: (2023)

Coccydynia Treated with Dorsal Root Ganglion Stimulation
por: Giordano, Nicholas L., et al.
Publicado: (2018)

Dorsal Root Ganglion (DRG) and Chronic Pain
por: Berger, Amnon A., et al.
Publicado: (2021)

Mitochondrial superoxide increases excitatory synaptic strength in spinal dorsal horn neurons of neuropathic mice
por: Bae, Chilman, et al.
Publicado: (2018)

Expression of cholecystokinin by neurons in mouse spinal dorsal horn
por: Gutierrez‐Mecinas, Maria, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6u0th7a4a3aa6q7vlo2v0pk69f