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Endothelial cell transforming growth factor-β receptor activation causes tacrolimus-induced renal arteriolar hyalinosis

Arteriolar hyalinosis is a common histological finding in renal transplant recipients treated with the calcineurin inhibitor tacrolimus; however, the pathophysiologic mechanisms remain unknown. In addition to increasing transforming growth factor (TGF)-β levels, tacrolimus inhibits calcineurin by bi...

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Detalles Bibliográficos
Autores principales:	Chiasson, Valorie L., Jones, Kathleen A., Kopriva, Shelley E., Mahajan, Ashutosh, Young, Kristina J., Mitchell, Brett M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396764/ https://www.ncbi.nlm.nih.gov/pubmed/22495293 http://dx.doi.org/10.1038/ki.2012.104

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