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Optic Atrophy 1-Dependent Mitochondrial Remodeling Controls Steroidogenesis in Trophoblasts

During human pregnancy, placental trophoblasts differentiate and syncytialize into syncytiotrophoblasts that sustain progesterone production [1]. This process is accompanied by mitochondrial fragmentation and cristae remodeling [2], two facets of mitochondrial apoptosis, whose molecular mechanisms a...

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Detalles Bibliográficos
Autores principales: Wasilewski, Michał, Semenzato, Martina, Rafelski, Susanne M., Robbins, Jennifer, Bakardjiev, Anna I., Scorrano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396839/
https://www.ncbi.nlm.nih.gov/pubmed/22658590
http://dx.doi.org/10.1016/j.cub.2012.04.054