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Optic Atrophy 1-Dependent Mitochondrial Remodeling Controls Steroidogenesis in Trophoblasts
During human pregnancy, placental trophoblasts differentiate and syncytialize into syncytiotrophoblasts that sustain progesterone production [1]. This process is accompanied by mitochondrial fragmentation and cristae remodeling [2], two facets of mitochondrial apoptosis, whose molecular mechanisms a...
Autores principales: | Wasilewski, Michał, Semenzato, Martina, Rafelski, Susanne M., Robbins, Jennifer, Bakardjiev, Anna I., Scorrano, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396839/ https://www.ncbi.nlm.nih.gov/pubmed/22658590 http://dx.doi.org/10.1016/j.cub.2012.04.054 |
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