SD118-Xanthocillin X (1), a Novel Marine Agent Extracted from Penicillium commune, Induces Autophagy through the Inhibition of the MEK/ERK Pathway

A compound named SD118-xanthocillin X (1) (C(18)H(12)N(2)O(2)), isolated from Penicillium commune in a deep-sea sediment sample, has been shown to inhibit the growth of several cancer cell lines in vitro. In the present study, we employed a growth inhibition assay and apoptotic analysis to identify...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Chen, Huan, Shang, Zhuo, Jiao, Binghua, Yuan, Bin, Sun, Weizhang, Wang, Bingui, Miao, Mingyong, Huang, Caiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397444/
https://www.ncbi.nlm.nih.gov/pubmed/22822377
http://dx.doi.org/10.3390/md10061345

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