Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral

Two new briarane diterpenoids, briarenolides, F (1) and G (2), were isolated from an octocoral identified as Briareum sp. The structures of briaranes 1 and 2 were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide F w...

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Autores principales: Hong, Pei-Han, Su, Yin-Di, Su, Jui-Hsin, Chen, Yung-Husan, Hwang, Tsong-Long, Weng, Ching-Feng, Lee, Chia-Hung, Wen, Zhi-Hong, Sheu, Jyh-Horng, Lin, Nai-Cheng, Kuo, Yueh-Hsiung, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397458/
https://www.ncbi.nlm.nih.gov/pubmed/22822363
http://dx.doi.org/10.3390/md10051156
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author Hong, Pei-Han
Su, Yin-Di
Su, Jui-Hsin
Chen, Yung-Husan
Hwang, Tsong-Long
Weng, Ching-Feng
Lee, Chia-Hung
Wen, Zhi-Hong
Sheu, Jyh-Horng
Lin, Nai-Cheng
Kuo, Yueh-Hsiung
Sung, Ping-Jyun
author_facet Hong, Pei-Han
Su, Yin-Di
Su, Jui-Hsin
Chen, Yung-Husan
Hwang, Tsong-Long
Weng, Ching-Feng
Lee, Chia-Hung
Wen, Zhi-Hong
Sheu, Jyh-Horng
Lin, Nai-Cheng
Kuo, Yueh-Hsiung
Sung, Ping-Jyun
author_sort Hong, Pei-Han
collection PubMed
description Two new briarane diterpenoids, briarenolides, F (1) and G (2), were isolated from an octocoral identified as Briareum sp. The structures of briaranes 1 and 2 were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide F was proven to be the first 6-hydroperoxybriarane derivative and this compound displayed a significant inhibitory effect on the generation of superoxide anion by human neutrophils.
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spelling pubmed-33974582012-07-20 Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral Hong, Pei-Han Su, Yin-Di Su, Jui-Hsin Chen, Yung-Husan Hwang, Tsong-Long Weng, Ching-Feng Lee, Chia-Hung Wen, Zhi-Hong Sheu, Jyh-Horng Lin, Nai-Cheng Kuo, Yueh-Hsiung Sung, Ping-Jyun Mar Drugs Article Two new briarane diterpenoids, briarenolides, F (1) and G (2), were isolated from an octocoral identified as Briareum sp. The structures of briaranes 1 and 2 were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide F was proven to be the first 6-hydroperoxybriarane derivative and this compound displayed a significant inhibitory effect on the generation of superoxide anion by human neutrophils. MDPI 2012-05-23 /pmc/articles/PMC3397458/ /pubmed/22822363 http://dx.doi.org/10.3390/md10051156 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Hong, Pei-Han
Su, Yin-Di
Su, Jui-Hsin
Chen, Yung-Husan
Hwang, Tsong-Long
Weng, Ching-Feng
Lee, Chia-Hung
Wen, Zhi-Hong
Sheu, Jyh-Horng
Lin, Nai-Cheng
Kuo, Yueh-Hsiung
Sung, Ping-Jyun
Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral
title Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral
title_full Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral
title_fullStr Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral
title_full_unstemmed Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral
title_short Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral
title_sort briarenolides f and g, new briarane diterpenoids from a briareum sp. octocoral
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397458/
https://www.ncbi.nlm.nih.gov/pubmed/22822363
http://dx.doi.org/10.3390/md10051156
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