Structure Elucidation and Anticancer Activity of 7-Oxostaurosporine Derivatives from the Brazilian Endemic Tunicate Eudistoma vannamei

The present study reports the identification of two new staurosporine derivatives, 2-hydroxy-7-oxostaurosporine (1) and 3-hydroxy-7-oxostaurosporine (2), obtained from mid-polar fractions of an aqueous methanol extract of the tunicate Eudistoma vannamei, endemic to the northeast coast of Brazil. The...

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Detalles Bibliográficos
Autores principales: Jimenez, Paula Christine, Wilke, Diego Veras, Ferreira, Elthon Gois, Takeara, Renata, de Moraes, Manoel Odorico, da Silveira, Edilberto Rocha, da Cruz Lotufo, Tito Monteiro, Lopes, Norberto Peporine, Costa-Lotufo, Leticia Veras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397465/
https://www.ncbi.nlm.nih.gov/pubmed/22822359
http://dx.doi.org/10.3390/md10051092

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