Evaluation of the Antioxidant Capacity of Synthesized Coumarins

Coumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picr...

Descripción completa

Detalles Bibliográficos
Autores principales: Vianna, Damiana R., Bubols, Guilherme, Meirelles, Gabriela, Silva, Bárbara V., da Rocha, Alessandra, Lanznaster, Maurício, Monserrat, José Maria, Garcia, Solange Cristina, von Poser, Gilsane, Eifler-Lima, Vera Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397524/
https://www.ncbi.nlm.nih.gov/pubmed/22837692
http://dx.doi.org/10.3390/ijms13067260
Descripción
Sumario:Coumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picryl-hydrazyl (DPPH(•)) method, cyclic voltammetry and the antioxidant capacity against peroxyl radicals (ACAP) method. The 7,8-dihydroxy-4-methylcoumarin (LaSOM 78), 5-carboxy-7,8-dihydroxy-4-methylcoumarin (LaSOM 79), and 6,7-dihydroxycoumarin (Esculetin) compounds proved to be the most active, showing the highest capacity to deplete the DPPH radicals, the highest antioxidant capacity against peroxyl radicals, and the lowest values of potential oxidation.

Ejemplares similares