Evaluation of the Antioxidant Capacity of Synthesized Coumarins

Coumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picr...

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Autores principales: Vianna, Damiana R., Bubols, Guilherme, Meirelles, Gabriela, Silva, Bárbara V., da Rocha, Alessandra, Lanznaster, Maurício, Monserrat, José Maria, Garcia, Solange Cristina, von Poser, Gilsane, Eifler-Lima, Vera Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397524/
https://www.ncbi.nlm.nih.gov/pubmed/22837692
http://dx.doi.org/10.3390/ijms13067260
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author Vianna, Damiana R.
Bubols, Guilherme
Meirelles, Gabriela
Silva, Bárbara V.
da Rocha, Alessandra
Lanznaster, Maurício
Monserrat, José Maria
Garcia, Solange Cristina
von Poser, Gilsane
Eifler-Lima, Vera Lucia
author_facet Vianna, Damiana R.
Bubols, Guilherme
Meirelles, Gabriela
Silva, Bárbara V.
da Rocha, Alessandra
Lanznaster, Maurício
Monserrat, José Maria
Garcia, Solange Cristina
von Poser, Gilsane
Eifler-Lima, Vera Lucia
author_sort Vianna, Damiana R.
collection PubMed
description Coumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picryl-hydrazyl (DPPH(•)) method, cyclic voltammetry and the antioxidant capacity against peroxyl radicals (ACAP) method. The 7,8-dihydroxy-4-methylcoumarin (LaSOM 78), 5-carboxy-7,8-dihydroxy-4-methylcoumarin (LaSOM 79), and 6,7-dihydroxycoumarin (Esculetin) compounds proved to be the most active, showing the highest capacity to deplete the DPPH radicals, the highest antioxidant capacity against peroxyl radicals, and the lowest values of potential oxidation.
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spelling pubmed-33975242012-07-26 Evaluation of the Antioxidant Capacity of Synthesized Coumarins Vianna, Damiana R. Bubols, Guilherme Meirelles, Gabriela Silva, Bárbara V. da Rocha, Alessandra Lanznaster, Maurício Monserrat, José Maria Garcia, Solange Cristina von Poser, Gilsane Eifler-Lima, Vera Lucia Int J Mol Sci Article Coumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picryl-hydrazyl (DPPH(•)) method, cyclic voltammetry and the antioxidant capacity against peroxyl radicals (ACAP) method. The 7,8-dihydroxy-4-methylcoumarin (LaSOM 78), 5-carboxy-7,8-dihydroxy-4-methylcoumarin (LaSOM 79), and 6,7-dihydroxycoumarin (Esculetin) compounds proved to be the most active, showing the highest capacity to deplete the DPPH radicals, the highest antioxidant capacity against peroxyl radicals, and the lowest values of potential oxidation. Molecular Diversity Preservation International (MDPI) 2012-06-13 /pmc/articles/PMC3397524/ /pubmed/22837692 http://dx.doi.org/10.3390/ijms13067260 Text en © 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Vianna, Damiana R.
Bubols, Guilherme
Meirelles, Gabriela
Silva, Bárbara V.
da Rocha, Alessandra
Lanznaster, Maurício
Monserrat, José Maria
Garcia, Solange Cristina
von Poser, Gilsane
Eifler-Lima, Vera Lucia
Evaluation of the Antioxidant Capacity of Synthesized Coumarins
title Evaluation of the Antioxidant Capacity of Synthesized Coumarins
title_full Evaluation of the Antioxidant Capacity of Synthesized Coumarins
title_fullStr Evaluation of the Antioxidant Capacity of Synthesized Coumarins
title_full_unstemmed Evaluation of the Antioxidant Capacity of Synthesized Coumarins
title_short Evaluation of the Antioxidant Capacity of Synthesized Coumarins
title_sort evaluation of the antioxidant capacity of synthesized coumarins
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397524/
https://www.ncbi.nlm.nih.gov/pubmed/22837692
http://dx.doi.org/10.3390/ijms13067260
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