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Contribution of Hypothermia and CB(1) Receptor Activation to Protective Effects of TAK-937, a Cannabinoid Receptor Agonist, in Rat Transient MCAO Model

BACKGROUND: Cannabinoid (CB) receptor agonists are expected to alleviate ischemic brain damage by modulating neurotransmission and neuroinflammatory responses via CB(1) and CB(2) receptors, respectively. In a previous study, TAK-937, a novel potent and selective CB(1) and CB(2) receptor agonist, was...

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Detalles Bibliográficos
Autores principales:	Suzuki, Noriko, Suzuki, Motohisa, Hamajo, Kazuhiro, Murakami, Koji, Tsukamoto, Tetsuya, Shimojo, Masato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397930/ https://www.ncbi.nlm.nih.gov/pubmed/22815855 http://dx.doi.org/10.1371/journal.pone.0040889

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