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Innate Immune Activation by Inhaled Lipopolysaccharide, Independent of Oxidative Stress, Exacerbates Silica-Induced Pulmonary Fibrosis in Mice
Acute exacerbations of pulmonary fibrosis are characterized by rapid decrements in lung function. Environmental factors that may contribute to acute exacerbations remain poorly understood. We have previously demonstrated that exposure to inhaled lipopolysaccharide (LPS) induces expression of genes a...
Autores principales: | Brass, David M., Spencer, Jennifer C., Li, Zhuowei, Potts-Kant, Erin, Reilly, Sarah M., Dunkel, Mary K., Latoche, Joseph D., Auten, Richard L., Hollingsworth, John W., Fattman, Cheryl L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397936/ https://www.ncbi.nlm.nih.gov/pubmed/22815821 http://dx.doi.org/10.1371/journal.pone.0040789 |
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