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N-Acetylcysteine Protects Rats with Chronic Renal Failure from Gadolinium-Chelate Nephrotoxicity

The aim of this study was to evaluate the effect of Gd-chelate on renal function, iron parameters and oxidative stress in rats with CRF and a possible protective effect of the antioxidant N-Acetylcysteine (NAC). Male Wistar rats were submitted to 5/6 nephrectomy (Nx) to induced CRF. An ionic - cycli...

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Detalles Bibliográficos
Autores principales:	Pereira, Leonardo Victor Barbosa, Shimizu, Maria Heloisa Massola, Rodrigues, Lina Paola Miranda Ruiz, Leite, Cláudia Costa, Andrade, Lúcia, Seguro, Antonio Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397987/ https://www.ncbi.nlm.nih.gov/pubmed/22815709 http://dx.doi.org/10.1371/journal.pone.0039528

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