BF066, a Novel Dual Target Antiplatelet Agent without Significant Bleeding

In this study, we report BF066, a novel adenine derivative, inhibits platelet activation and thrombosis via the adenosine receptor (A(2A)) activation and phosphodiesterase (PDE) inhibition. BF066 inhibits platelet aggregation and ATP releasing induced by multiple platelet agonists in a dose-dependen...

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Detalles Bibliográficos
Autores principales: Pan, ChangE, Wei, Xunbin, Ye, Jianqin, Liu, Guangda, Zhang, Si, Zhang, Yan, Du, Hongguang, Ding, Zhongren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398006/
https://www.ncbi.nlm.nih.gov/pubmed/22815749
http://dx.doi.org/10.1371/journal.pone.0040451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398006/
https://www.ncbi.nlm.nih.gov/pubmed/22815749
http://dx.doi.org/10.1371/journal.pone.0040451

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