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Alleviation of Gut Inflammation by Cdx2/Pxr Pathway in a Mouse Model of Chemical Colitis
Pregnane X Receptor (PXR), a master regulator of drug metabolism and inflammation, is abundantly expressed in the gastrointestinal tract. Baicalein and its O-glucuronide baicalin are potent anti-inflammatory and anti-cancer herbal flavonoids that undergo a complex cycle of interconversion in the liv...
Autores principales: | Dou, Wei, Mukherjee, Subhajit, Li, Hao, Venkatesh, Madhukumar, Wang, Hongwei, Kortagere, Sandhya, Peleg, Ariel, Chilimuri, Sridhar S., Wang, Zheng-Tao, Feng, Ying, Fearon, Eric R., Mani, Sridhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398007/ https://www.ncbi.nlm.nih.gov/pubmed/22815676 http://dx.doi.org/10.1371/journal.pone.0036075 |
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