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Myeloid Suppressor Cell Depletion Augments Antitumor Activity in Lung Cancer

BACKGROUND: Myeloid derived suppressor cells (MDSC) are important regulators of immune responses. We evaluated the mechanistic role of MDSC depletion on antigen presenting cell (APC), NK, T cell activities and therapeutic vaccination responses in murine models of lung cancer. PRINCIPAL FINDINGS: Ind...

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Detalles Bibliográficos
Autores principales:	Srivastava, Minu K., Zhu, Li, Harris-White, Marni, Kar, Upendra, Huang, Min, Johnson, Ming F., Lee, Jay M., Elashoff, David, Strieter, Robert, Dubinett, Steven, Sharma, Sherven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398024/ https://www.ncbi.nlm.nih.gov/pubmed/22815789 http://dx.doi.org/10.1371/journal.pone.0040677

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