Transfer of Ho Endonuclease and Ufo1 to the Proteasome by the UbL-UbA Shuttle Protein, Ddi1, Analysed by Complex Formation In Vitro

The F-box protein, Ufo1, recruits Ho endonuclease to the SCF(Ufo1) complex for ubiquitylation. Both ubiquitylated Ho and Ufo1 are transferred by the UbL-UbA protein, Ddi1, to the 19S Regulatory Particle (RP) of the proteasome for degradation. The Ddi1-UbL domain binds Rpn1 of the 19S RP, the Ddi1-Ub...

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Detalles Bibliográficos
Autores principales: Voloshin, Olga, Bakhrat, Anya, Herrmann, Sharon, Raveh, Dina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398040/
https://www.ncbi.nlm.nih.gov/pubmed/22815701
http://dx.doi.org/10.1371/journal.pone.0039210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398040/
https://www.ncbi.nlm.nih.gov/pubmed/22815701
http://dx.doi.org/10.1371/journal.pone.0039210

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