Targeted Inactivation of GPR26 Leads to Hyperphagia and Adiposity by Activating AMPK in the Hypothalamus

G-protein coupled receptor 26 (GPR26) is a brain-specific orphan GPCR with high expression in the brain region that controls satiety. Depletion of GPR26 has been shown to increase fat storage in C. elegans, whereas GPR26 deficiency in the hypothalamus is associated with high genetic susceptibility t...

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Detalles Bibliográficos
Autores principales: Chen, Daohong, Liu, Xiaolei, Zhang, Weiping, Shi, Yuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398048/
https://www.ncbi.nlm.nih.gov/pubmed/22815809
http://dx.doi.org/10.1371/journal.pone.0040764

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