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Clues for Diagnosing Primary Pancreatic Lymphoma
Primary pancreatic lymphoma (PPL), a localized lymphoma in the pancreas, accounts for <0.5% of all pancreatic masses and presents with symptoms favoring the more common adenocarcinoma. It is important to differentiate PPL from adenocarcinoma since treatment and prognosis differ considerably. PPL...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398069/ https://www.ncbi.nlm.nih.gov/pubmed/22855659 http://dx.doi.org/10.1159/000339968 |
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author | Li, Zhongzhen Zhang, Shaoxiong Vasdani, Nadiya Castillo, Eddy |
author_facet | Li, Zhongzhen Zhang, Shaoxiong Vasdani, Nadiya Castillo, Eddy |
author_sort | Li, Zhongzhen |
collection | PubMed |
description | Primary pancreatic lymphoma (PPL), a localized lymphoma in the pancreas, accounts for <0.5% of all pancreatic masses and presents with symptoms favoring the more common adenocarcinoma. It is important to differentiate PPL from adenocarcinoma since treatment and prognosis differ considerably. PPL is potentially curable with chemotherapy, especially if it is diagnosed at early stages. A definitive diagnosis can only be based on histopathological findings. Endoscopic ultrasound-guided fine needle aspiration (EUS-guided FNA) is a reliable, minimally invasive and cost-effective method for this purpose. Even though there are neither typical clinical features nor specific biomarker for the diagnosis of PPL, certain common presentations have been observed which may indicate PPL. We herein present the case of a 43-year-old man who was successfully diagnosed with PPL by EUS-guided FNA. His clinical, laboratory and radiographic findings supported PPL over adenocarcinoma as well. This case demonstrates that high clinical suspicion based on clinical, laboratory and imaging features is critical in PPL diagnosis and management. |
format | Online Article Text |
id | pubmed-3398069 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-33980692012-08-01 Clues for Diagnosing Primary Pancreatic Lymphoma Li, Zhongzhen Zhang, Shaoxiong Vasdani, Nadiya Castillo, Eddy Case Rep Gastroenterol Published online: July, 2012 Primary pancreatic lymphoma (PPL), a localized lymphoma in the pancreas, accounts for <0.5% of all pancreatic masses and presents with symptoms favoring the more common adenocarcinoma. It is important to differentiate PPL from adenocarcinoma since treatment and prognosis differ considerably. PPL is potentially curable with chemotherapy, especially if it is diagnosed at early stages. A definitive diagnosis can only be based on histopathological findings. Endoscopic ultrasound-guided fine needle aspiration (EUS-guided FNA) is a reliable, minimally invasive and cost-effective method for this purpose. Even though there are neither typical clinical features nor specific biomarker for the diagnosis of PPL, certain common presentations have been observed which may indicate PPL. We herein present the case of a 43-year-old man who was successfully diagnosed with PPL by EUS-guided FNA. His clinical, laboratory and radiographic findings supported PPL over adenocarcinoma as well. This case demonstrates that high clinical suspicion based on clinical, laboratory and imaging features is critical in PPL diagnosis and management. S. Karger AG 2012-07-05 /pmc/articles/PMC3398069/ /pubmed/22855659 http://dx.doi.org/10.1159/000339968 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published online: July, 2012 Li, Zhongzhen Zhang, Shaoxiong Vasdani, Nadiya Castillo, Eddy Clues for Diagnosing Primary Pancreatic Lymphoma |
title | Clues for Diagnosing Primary Pancreatic Lymphoma |
title_full | Clues for Diagnosing Primary Pancreatic Lymphoma |
title_fullStr | Clues for Diagnosing Primary Pancreatic Lymphoma |
title_full_unstemmed | Clues for Diagnosing Primary Pancreatic Lymphoma |
title_short | Clues for Diagnosing Primary Pancreatic Lymphoma |
title_sort | clues for diagnosing primary pancreatic lymphoma |
topic | Published online: July, 2012 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398069/ https://www.ncbi.nlm.nih.gov/pubmed/22855659 http://dx.doi.org/10.1159/000339968 |
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