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Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Colitis

Radiation colitis is a common consequence of pelvic radiation. Its complications may include anemia due to chronic bleeding requiring transfusions. Many of these patients are managed with rectal medications which are often inadequate for control. Argon plasma coagulation (APC) has been well describe...

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Autores principales: Lam, Mindy C.W., Parliament, Matthew, Wong, Clarence K.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398092/
https://www.ncbi.nlm.nih.gov/pubmed/22933988
http://dx.doi.org/10.1159/000339462
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author Lam, Mindy C.W.
Parliament, Matthew
Wong, Clarence K.W.
author_facet Lam, Mindy C.W.
Parliament, Matthew
Wong, Clarence K.W.
author_sort Lam, Mindy C.W.
collection PubMed
description Radiation colitis is a common consequence of pelvic radiation. Its complications may include anemia due to chronic bleeding requiring transfusions. Many of these patients are managed with rectal medications which are often inadequate for control. Argon plasma coagulation (APC) has been well described for its efficacy in treating radiation proctitis. Here we present two cases in whom APC therapy was used to treat severe radiation colitis. We reviewed two cases originally seen at the regional cancer center (Cross Cancer Institute) in Edmonton, Alberta, Canada. Both patients received pelvic radiation for recurrent endometrial cancers and were referred for active bleeding secondary to radiation colitis that had required numerous transfusions. Radiation-induced telangiectasias were found from 10–50 cm in the sigmoid colon. Both patients had significant improvement of symptoms after one session of APC treatment set at 40–60 W and gas flow of 2.0 l/min. There were no complications from the procedures. Neither patient required blood transfusions after the treatment with improvement in their hemoglobin levels and were doing well at 3- and 6-month follow-up. APC can be used effectively to provide immediate and sustained resolution of symptoms in patients with radiation colitis.
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spelling pubmed-33980922012-08-29 Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Colitis Lam, Mindy C.W. Parliament, Matthew Wong, Clarence K.W. Case Rep Gastroenterol Published online: July, 2012 Radiation colitis is a common consequence of pelvic radiation. Its complications may include anemia due to chronic bleeding requiring transfusions. Many of these patients are managed with rectal medications which are often inadequate for control. Argon plasma coagulation (APC) has been well described for its efficacy in treating radiation proctitis. Here we present two cases in whom APC therapy was used to treat severe radiation colitis. We reviewed two cases originally seen at the regional cancer center (Cross Cancer Institute) in Edmonton, Alberta, Canada. Both patients received pelvic radiation for recurrent endometrial cancers and were referred for active bleeding secondary to radiation colitis that had required numerous transfusions. Radiation-induced telangiectasias were found from 10–50 cm in the sigmoid colon. Both patients had significant improvement of symptoms after one session of APC treatment set at 40–60 W and gas flow of 2.0 l/min. There were no complications from the procedures. Neither patient required blood transfusions after the treatment with improvement in their hemoglobin levels and were doing well at 3- and 6-month follow-up. APC can be used effectively to provide immediate and sustained resolution of symptoms in patients with radiation colitis. S. Karger AG 2012-07-05 /pmc/articles/PMC3398092/ /pubmed/22933988 http://dx.doi.org/10.1159/000339462 Text en Copyright © 2012 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: July, 2012
Lam, Mindy C.W.
Parliament, Matthew
Wong, Clarence K.W.
Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Colitis
title Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Colitis
title_full Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Colitis
title_fullStr Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Colitis
title_full_unstemmed Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Colitis
title_short Argon Plasma Coagulation for the Treatment of Hemorrhagic Radiation Colitis
title_sort argon plasma coagulation for the treatment of hemorrhagic radiation colitis
topic Published online: July, 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398092/
https://www.ncbi.nlm.nih.gov/pubmed/22933988
http://dx.doi.org/10.1159/000339462
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