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A dynamic model of circadian rhythms in rodent tail skin temperature for comparison of drug effects
Menopause-associated thermoregulatory dysfunction can lead to symptoms such as hot flushes severely impairing quality of life of affected women. Treatment effects are often assessed by the ovariectomized rat model providing time series of tail skin temperature measurements in which circadian rhythms...
Autores principales: | Girbig, Dorothee, Keller, Karsten, Prelle, Katja, Patchev, Vladimir, Vonk, Richardus, Igl, Bernd-Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398330/ https://www.ncbi.nlm.nih.gov/pubmed/22221596 http://dx.doi.org/10.1186/1740-3391-10-1 |
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