Spatial expression patterns of autophagy genes in the eye lens and induction of autophagy in lens cells

PURPOSE: Mutation of the autophagy gene FYVE (named after the four cysteine-rich proteins: Fab 1 [yeast orthologue of PIKfyve], YOTB, Vac 1 [vesicle transport protein], and EEA1) and coiled coil containing 1 (fyco1) causes human cataract suggesting a role for autophagy in lens function. Here, we ana...

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Detalles Bibliográficos
Autores principales: Brennan, Lisa Ann, Kantorow, Wanda Lee, Chauss, Daniel, McGreal, Rebecca, He, Shuying, Mattucci, Lyndzie, Wei, Jianning, Riazuddin, S. Amer, Cvekl, Ales, Hejtmancik, J. Fielding, Kantorow, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398491/
https://www.ncbi.nlm.nih.gov/pubmed/22815631

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