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SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU)
PURPOSE: SWAP 70-like adaptor of T cells (SLAT; aka Def6) is a recently discovered guanine nucleotide exchange factor for Rho guanosine triphosphate (GTP)ases that has been previously shown to play a role in cluster of differentiation(CD)4+ T cell activation, T-helper (Th)1/Th2/Th17 differentiation...
Autores principales: | Vistica, Barbara P., Shi, Guangpu, Nugent, Lindsey, Tan, Cuiyan, Altman, Amnon, Gery, Igal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398495/ https://www.ncbi.nlm.nih.gov/pubmed/22815639 |
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