Quiescent keratocytes fail to repair MMC induced DNA damage leading to the long-term inhibition of myofibroblast differentiation and wound healing

PURPOSE: The purpose of this study was to determine the acute and long-term effects of mitomycin C (MMC) on quiescent rabbit corneal keratocytes regarding cell proliferation, myofibroblast differentiation and DNA repair. METHODS: Quiescent keratocytes cultured in serum-free media were exposed to var...

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Detalles Bibliográficos
Autores principales: Jester, James V., Nien, Chyong Jy, Vasiliou, Vasilis, Brown, Donald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398499/
https://www.ncbi.nlm.nih.gov/pubmed/22815636

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