In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors

Most antiretroviral medical treatments were developed and tested principally on HIV-1 B nonrecombinant strain, which represents less than 10% of the worldwide HIV-1-infected population. HIV-1 circulating recombinant form CRF02_AG is prevalent in West Africa and is becoming more frequent in other cou...

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Detalles Bibliográficos
Autores principales: Ni, Xiaoju, Abdel-Azeim, Safwat, Laine, Elodie, Arora, Rohit, Osemwota, Osamuede, Marcelin, Anne-Geneviève, Calvez, Vincent, Mouscadet, Jean-François, Tchertanov, Luba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398581/
https://www.ncbi.nlm.nih.gov/pubmed/22829822
http://dx.doi.org/10.1155/2012/548657

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