Cargando…

Adolescent Metabolic Syndrome Risk Is Increased with Higher Infancy Weight Gain and Decreased with Longer Breast Feeding

Background. Prevalence of the metabolic syndrome is increasing in pediatric age groups worldwide. Meeting the criteria for the metabolic syndrome puts children at risk for later cardiovascular and metabolic disease. Methods. Using linear regression, we examined the association between infant weight...

Descripción completa

Detalles Bibliográficos
Autores principales: Khuc, Kim, Blanco, Estela, Burrows, Raquel, Reyes, Marcela, Castillo, Marcela, Lozoff, Betsy, Gahagan, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398649/
https://www.ncbi.nlm.nih.gov/pubmed/22829844
http://dx.doi.org/10.1155/2012/478610
_version_ 1782238311116439552
author Khuc, Kim
Blanco, Estela
Burrows, Raquel
Reyes, Marcela
Castillo, Marcela
Lozoff, Betsy
Gahagan, Sheila
author_facet Khuc, Kim
Blanco, Estela
Burrows, Raquel
Reyes, Marcela
Castillo, Marcela
Lozoff, Betsy
Gahagan, Sheila
author_sort Khuc, Kim
collection PubMed
description Background. Prevalence of the metabolic syndrome is increasing in pediatric age groups worldwide. Meeting the criteria for the metabolic syndrome puts children at risk for later cardiovascular and metabolic disease. Methods. Using linear regression, we examined the association between infant weight gain from birth to 3 months and risk for the metabolic syndrome among 16- to 17-year-old Chilean adolescents (n = 357), accounting for the extent of breastfeeding in infancy and known covariates including gender, birth weight, and socioeconomic status. Results. Participants were approximately half male (51%), born at 40 weeks of gestation weighing 3.5 kg, and 48% were exclusively breastfed for ≥90 days. Factors independently associated with increased risk of metabolic syndrome in adolescence were faster weight gain in the first 3 months of life (B = 0.16, P < 0.05) and male gender (B = 0.24, P < 0.05). Breastfeeding as the sole source of milk for ≥90 days was associated with significantly decreased risk of metabolic syndrome (B = −0.16). Conclusion. This study adds to current knowledge about early infant growth and breastfeeding and their long-term health effects.
format Online
Article
Text
id pubmed-3398649
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-33986492012-07-24 Adolescent Metabolic Syndrome Risk Is Increased with Higher Infancy Weight Gain and Decreased with Longer Breast Feeding Khuc, Kim Blanco, Estela Burrows, Raquel Reyes, Marcela Castillo, Marcela Lozoff, Betsy Gahagan, Sheila Int J Pediatr Research Article Background. Prevalence of the metabolic syndrome is increasing in pediatric age groups worldwide. Meeting the criteria for the metabolic syndrome puts children at risk for later cardiovascular and metabolic disease. Methods. Using linear regression, we examined the association between infant weight gain from birth to 3 months and risk for the metabolic syndrome among 16- to 17-year-old Chilean adolescents (n = 357), accounting for the extent of breastfeeding in infancy and known covariates including gender, birth weight, and socioeconomic status. Results. Participants were approximately half male (51%), born at 40 weeks of gestation weighing 3.5 kg, and 48% were exclusively breastfed for ≥90 days. Factors independently associated with increased risk of metabolic syndrome in adolescence were faster weight gain in the first 3 months of life (B = 0.16, P < 0.05) and male gender (B = 0.24, P < 0.05). Breastfeeding as the sole source of milk for ≥90 days was associated with significantly decreased risk of metabolic syndrome (B = −0.16). Conclusion. This study adds to current knowledge about early infant growth and breastfeeding and their long-term health effects. Hindawi Publishing Corporation 2012 2012-07-05 /pmc/articles/PMC3398649/ /pubmed/22829844 http://dx.doi.org/10.1155/2012/478610 Text en Copyright © 2012 Kim Khuc et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Khuc, Kim
Blanco, Estela
Burrows, Raquel
Reyes, Marcela
Castillo, Marcela
Lozoff, Betsy
Gahagan, Sheila
Adolescent Metabolic Syndrome Risk Is Increased with Higher Infancy Weight Gain and Decreased with Longer Breast Feeding
title Adolescent Metabolic Syndrome Risk Is Increased with Higher Infancy Weight Gain and Decreased with Longer Breast Feeding
title_full Adolescent Metabolic Syndrome Risk Is Increased with Higher Infancy Weight Gain and Decreased with Longer Breast Feeding
title_fullStr Adolescent Metabolic Syndrome Risk Is Increased with Higher Infancy Weight Gain and Decreased with Longer Breast Feeding
title_full_unstemmed Adolescent Metabolic Syndrome Risk Is Increased with Higher Infancy Weight Gain and Decreased with Longer Breast Feeding
title_short Adolescent Metabolic Syndrome Risk Is Increased with Higher Infancy Weight Gain and Decreased with Longer Breast Feeding
title_sort adolescent metabolic syndrome risk is increased with higher infancy weight gain and decreased with longer breast feeding
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398649/
https://www.ncbi.nlm.nih.gov/pubmed/22829844
http://dx.doi.org/10.1155/2012/478610
work_keys_str_mv AT khuckim adolescentmetabolicsyndromeriskisincreasedwithhigherinfancyweightgainanddecreasedwithlongerbreastfeeding
AT blancoestela adolescentmetabolicsyndromeriskisincreasedwithhigherinfancyweightgainanddecreasedwithlongerbreastfeeding
AT burrowsraquel adolescentmetabolicsyndromeriskisincreasedwithhigherinfancyweightgainanddecreasedwithlongerbreastfeeding
AT reyesmarcela adolescentmetabolicsyndromeriskisincreasedwithhigherinfancyweightgainanddecreasedwithlongerbreastfeeding
AT castillomarcela adolescentmetabolicsyndromeriskisincreasedwithhigherinfancyweightgainanddecreasedwithlongerbreastfeeding
AT lozoffbetsy adolescentmetabolicsyndromeriskisincreasedwithhigherinfancyweightgainanddecreasedwithlongerbreastfeeding
AT gahagansheila adolescentmetabolicsyndromeriskisincreasedwithhigherinfancyweightgainanddecreasedwithlongerbreastfeeding