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FunSys: Software for functional analysis of prokaryotic transcriptome and proteome

The vast amount of data produced by next-generation sequencing (NGS) has necessitated the development of computational tools to assist in understanding the myriad functions performed by the biological macromolecules involved in heredity. In this work, we developed the FunSys programme, a stand-alone...

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Detalles Bibliográficos
Autores principales: de Sá, Pablo, Pinto, Anne, Ramos, Rommel Thiago Jucá, Coimbra, Nilson, Baraúna, Rafael, Dall'Agnol, Hivana, Carneiro, Adriana, Ranieri, Alex, Valadares, Agenor, Azevedo, Vasco, Schneider, Maria Paula, Barh, Debmalya, Silva, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398771/
https://www.ncbi.nlm.nih.gov/pubmed/22829724
http://dx.doi.org/10.6026/97320630008529
Descripción
Sumario:The vast amount of data produced by next-generation sequencing (NGS) has necessitated the development of computational tools to assist in understanding the myriad functions performed by the biological macromolecules involved in heredity. In this work, we developed the FunSys programme, a stand-alone tool with an user friendly interface that enables us to evaluate and correlate differential expression patterns from RNA sequencing and proteomics datasets. The FunSys generates charts and reports based on the results of the analysis of differential expression to aid the interpretation of the results. AVAILABILITY: FunSys and a test dataset are freely available at https://sourceforge.net/projects/funsysufpa/. It requires Sun jdk 6 or higher and MySQL server 5.1 or higher.