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Bacterial genome mapper: A comparative bacterial genome mapping tool

Recently, next generation sequencing (NGS) technologies have led to a revolutionary increase in sequencing speed and costefficacy. Consequently, a vast number of contigs from many recently sequenced bacterial genomes remain to be accurately mapped and annotated, requiring the development of more con...

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Detalles Bibliográficos
Autores principales: Lee, Kang Seon, Kim, Ryong Nam, Yoon, Byoung Ha, Kim, Dae Soo, Choi, Sang Haeng, Kim, Dong Wook, Nam, Seong Hyeuk, Kim, Aeri, Kang, Aram, Park, Kun Hyang, Jung, Jae Eun, Chae, Sung Hwa, Park, Hong Seog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398773/
https://www.ncbi.nlm.nih.gov/pubmed/22829725
http://dx.doi.org/10.6026/97320630008532
Descripción
Sumario:Recently, next generation sequencing (NGS) technologies have led to a revolutionary increase in sequencing speed and costefficacy. Consequently, a vast number of contigs from many recently sequenced bacterial genomes remain to be accurately mapped and annotated, requiring the development of more convenient bioinformatics programs. In this paper, we present a newly developed web-based bioinformatics program, Bacterial Genome Mapper, which is suitable for mapping and annotating contigs that have been assembled from bacterial genome sequence raw data. By constructing a multiple alignment map between target contig sequences and two reference bacterial genome sequences, this program also provides very useful comparative genomics analysis of draft bacterial genomes. AVAILABILITY: Bacterial Genome Mapper is freely accessible at http://mbgm.kribb.re.kr