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Vitamin E Isoforms Differentially Regulate Intercellular Adhesion Molecule-1 Activation of PKCα in Human Microvascular Endothelial Cells

AIMS: ICAM-1-dependent leukocyte recruitment in vivo is inhibited by the vitamin E isoform d-α-tocopherol and elevated by d-γ-tocopherol. ICAM-1 is reported to activate endothelial cell signals including protein kinase C (PKC), but the PKC isoform and the mechanism for ICAM-1 activation of PKC are n...

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Detalles Bibliográficos
Autores principales:	Abdala-Valencia, Hiam, Berdnikovs, Sergejs, Cook-Mills, Joan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398863/ https://www.ncbi.nlm.nih.gov/pubmed/22815910 http://dx.doi.org/10.1371/journal.pone.0041054

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