The Inositol Phosphatase SHIP-1 Inhibits NOD2-Induced NF-κB Activation by Disturbing the Interaction of XIAP with RIP2

SHIP-1 is an inositol phosphatase predominantly expressed in hematopoietic cells. Over the ten past years, SHIP-1 has been described as an important regulator of immune functions. Here, we characterize a new inhibitory function for SHIP-1 in NOD2 signaling. NOD2 is a crucial cytoplasmic bacterial se...

Descripción completa

Detalles Bibliográficos
Autores principales: Condé, Claude, Rambout, Xavier, Lebrun, Marielle, Lecat, Aurore, Di Valentin, Emmanuel, Dequiedt, Franck, Piette, Jacques, Gloire, Geoffrey, Legrand, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398883/
https://www.ncbi.nlm.nih.gov/pubmed/22815893
http://dx.doi.org/10.1371/journal.pone.0041005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398883/
https://www.ncbi.nlm.nih.gov/pubmed/22815893
http://dx.doi.org/10.1371/journal.pone.0041005

Ejemplares similares