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VAPC, an Human Endogenous Inhibitor for Hepatitis C Virus (HCV) Infection, Is Intrinsically Unstructured but Forms a “Fuzzy Complex” with HCV NS5B
Nearly 200 million people are infected by hepatitis C virus (HCV) worldwide. For replicating the HCV genome, the membrane-associated machinery needs to be formed by both HCV non-structural proteins (including NS5B) and human host factors such as VAPB. Recently, the 99-residue VAPC, a splicing varian...
Autores principales: | Goyal, Shaveta, Gupta, Garvita, Qin, Haina, Upadya, Megha Haridas, Tan, Yee Joo, Chow, Vincent T. K., Song, Jianxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398895/ https://www.ncbi.nlm.nih.gov/pubmed/22815741 http://dx.doi.org/10.1371/journal.pone.0040341 |
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