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Gemcitabine and Irinotecan as First-Line Therapy for Carcinoma of Unknown Primary: Results of a Multicenter Phase II Trial
Metastatic carcinoma of unknown primary (CUP) has a very poor prognosis, and no standard first-line therapy currently exists. Here, we report the results of a phase II study utilizing a combination of gemcitabine and irinotecan as first-line therapy. Treatment was with gemcitabine 1000 mg/m(2) and i...
Autores principales: | Holtan, Shernan G., Steen, Preston D., Foster, Nathan R., Erlichman, Charles, Medeiros, Fabiola, Ames, Matthew M., Safgren, Stephanie L., Graham, David L., Behrens, Robert J., Goetz, Matthew P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398897/ https://www.ncbi.nlm.nih.gov/pubmed/22815703 http://dx.doi.org/10.1371/journal.pone.0039285 |
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