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DSP-PP Precursor Protein Cleavage by Tolloid-Related-1 Protein and by Bone Morphogenetic Protein-1

Dentin sialoprotein (DSP) and phosphophoryn (PP), acidic proteins critical to dentin mineralization, are translated from a single transcript as a DSP-PP precursor that undergoes specific proteolytic processing to generate DSP and PP. The cleavage mechanism continues to be controversial, in part beca...

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Detalles Bibliográficos
Autores principales: Ritchie, Helena H., Yee, Colin T., Tang, Xu-na, Dong, Zhihong, Fuller, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398931/
https://www.ncbi.nlm.nih.gov/pubmed/22815932
http://dx.doi.org/10.1371/journal.pone.0041110