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Signal 3 Cytokines as Modulators of Primary Immune Responses during Infections: The Interplay of Type I IFN and IL-12 in CD8 T Cell Responses

Signal 3 cytokines, such as IL-12 or type I IFN, support expansion and differentiation of CD8 T cells in vivo. If and how these two signal 3 cytokines compensate each other in T cell activation during different infections is so far unknown. Using CD8 T cells lacking receptors for IL-12, type I IFN o...

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Detalles Bibliográficos
Autores principales:	Keppler, Selina Jessica, Rosenits, Kerstin, Koegl, Tamara, Vucikuja, Smiljka, Aichele, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398954/ https://www.ncbi.nlm.nih.gov/pubmed/22815848 http://dx.doi.org/10.1371/journal.pone.0040865

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