Cargando…

Enhancement of Closed-State Inactivation by Neutralization of S4 Arginines in Domain IV of a Sodium Channel

Detalles Bibliográficos
Autor principal:	Paldi, Tzur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3399128/ https://www.ncbi.nlm.nih.gov/pubmed/22826699 http://dx.doi.org/10.3389/fphar.2012.00143

Ejemplares similares

Role of the voltage sensor module in Na(v) domain IV on fast inactivation in sodium channelopathies: The implication of closed-state inactivation
por: Nakajima, Tadashi, et al.
Publicado: (2019)

MTSET modification of D4S6 cysteines stabilize the fast inactivated state of Na(v)1.5 sodium channels
por: O’Leary, Michael E., et al.
Publicado: (2015)

A Novel Spider Toxin Inhibits Fast Inactivation of the Na(v)1.9 Channel by Binding to Domain III and Domain IV Voltage Sensors
por: Peng, Shuijiao, et al.
Publicado: (2021)

Role of Domain 4 in Sodium Channel Slow Inactivation
por: Mitrovic, Nenad, et al.
Publicado: (2000)

Closed-state inactivation of cardiac, skeletal, and neuronal sodium channels is isoform specific
por: Brake, Niklas, et al.
Publicado: (2022)

Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels
por: Capes, Deborah L., et al.
Publicado: (2013)

A conformational change of the domain IV S6 segment of the voltage-gated sodium channel during inactivation
por: Gawali, Vaibhavkumar S, et al.
Publicado: (2012)

A unique role for the S4 segment of domain 4 in the inactivation of sodium channels
Publicado: (1996)

Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Na(v)1.4 Channel
por: Myshkin, Mikhail Yu., et al.
Publicado: (2019)

Voltage Sensor Inactivation in Potassium Channels
por: Bähring, Robert, et al.
Publicado: (2012)

Independent Versus Coupled Inactivation in Sodium Channels : Role of the Domain 2 S4 Segment
por: Mitrovic, Nenad, et al.
Publicado: (1998)

The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel Na(V)1.8 to Enhance Activation
por: Deuis, Jennifer R., et al.
Publicado: (2022)

A thermosensitive mutation alters the effects of lacosamide on slow inactivation in neuronal voltage-gated sodium channels, Na(V)1.2
por: Abdelsayed, Mena, et al.
Publicado: (2013)

Inactivation defects caused by myotonia-associated mutations in the sodium channel III-IV linker
Publicado: (1996)

Gating Charge Immobilization in Kv4.2 Channels: The Basis of Closed-State Inactivation
por: Dougherty, Kevin, et al.
Publicado: (2008)

Block of Voltage-Gated Sodium Channels by Atomoxetine in a State- and Use-dependent Manner
por: Föhr, Karl Josef, et al.
Publicado: (2021)

Possible Interactions of Extracellular Loop IVP2-S6 With Voltage-Sensing Domain III in Cardiac Sodium Channel
por: Zaytseva, Anastasia K., et al.
Publicado: (2021)

Structural model of the open–closed–inactivated cycle of prokaryotic voltage-gated sodium channels
por: Bagnéris, Claire, et al.
Publicado: (2015)

Sodium Channels as Targets for Volatile Anesthetics
por: Herold, Karl F., et al.
Publicado: (2012)

Fenestropathy of Voltage-Gated Sodium Channels
por: Gamal El-Din, Tamer M., et al.
Publicado: (2022)

Conformations of voltage-sensing domain III differentially define Na(V) channel closed- and open-state inactivation
por: Angsutararux, Paweorn, et al.
Publicado: (2021)

Novel Sodium Channel Inhibitor From Leeches
por: Wang, Gan, et al.
Publicado: (2018)

Structural Advances in Voltage-Gated Sodium Channels
por: Jiang, Daohua, et al.
Publicado: (2022)

Editorial: Pharmacology of L-Arginine and L-Arginine-Rich Food
por: Poeggeler, Burkhard, et al.
Publicado: (2021)

Movement of Voltage Sensor S4 in Domain 4 Is Tightly Coupled to Sodium Channel Fast Inactivation and Gating Charge Immobilization
por: Kühn, Frank J.P., et al.
Publicado: (1999)

Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels
por: Stevens, Marijke, et al.
Publicado: (2011)

The Sodium Channel as a Target for Local Anesthetic Drugs
por: Fozzard, Harry A., et al.
Publicado: (2011)

Inhibition of voltage-gated sodium channels by sumatriptan bioisosteres
por: Carbonara, Roberta, et al.
Publicado: (2015)

Molecular Pathology of Sodium Channel Beta-Subunit Variants
por: Angsutararux, Paweorn, et al.
Publicado: (2021)

Inactivation of the sodium channel. I. Sodium current experiments
por: Bezanilla, F, et al.
Publicado: (1977)

Dynamic Coupling of Voltage Sensor and Gate Involved in Closed-State Inactivation of Kv4.2 Channels
por: Barghaan, Jan, et al.
Publicado: (2009)

Sodium Channel Inactivation Goes with the Flow
por: Kass, Robert S.
Publicado: (2004)

Domain III S4 in closed-state fast inactivation: Insights from a periodic paralysis mutation
por: Groome, James R, et al.
Publicado: (2014)

The Hydrophobic Effect Contributes to the Closed State of a Simplified Ion Channel through a Conserved Hydrophobic Patch at the Pore-Helix Crossing
por: Yonkunas, Michael, et al.
Publicado: (2015)

Propranolol Blocks Cardiac and Neuronal Voltage-Gated Sodium Channels
por: Wang, Dao W., et al.
Publicado: (2010)

Voltage-Gated Sodium Channels: Biophysics, Pharmacology, and Related Channelopathies
por: Savio-Galimberti, Eleonora, et al.
Publicado: (2012)

Voltage-gated sodium channels and cancer: is excitability their primary role?
por: Roger, Sébastien, et al.
Publicado: (2015)

Sodium Channels and Local Anesthetics—Old Friends With New Perspectives
por: Körner, Jannis, et al.
Publicado: (2022)

Intersegment Contacts of Potentially Damaging Variants of Cardiac Sodium Channel
por: Korkosh, Vyacheslav S., et al.
Publicado: (2021)

Acidosis Differentially Modulates Inactivation in Na(V)1.2, Na(V)1.4, and Na(V)1.5 Channels
por: Vilin, Yury Y., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_mbslbmhta9fhh53ej9s5pigajf